1,1′-(1,2-ethynediyl)bis-benzene derivatives as PTP 1-B inhibitors
US7947851B2 · kind B2 · utility
0Cited by
3References
21Claims
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Key dates
| Filing date | Mar 29, 2005 |
| Grant date | May 24, 2011 |
| Priority date | — |
| Expiry date | Jul 25, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is related to carboxylic acids of Formula (I) and use thereof for the treatment and/or prevention of obesity and/or metabolic disorders mediated by insulin resistance or hyperglycemia, comprising diabetes type I and/or II, inadequate glucose tolerance, insulin resistance, hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, polycystic ovary syndrome (PCOS). In particular, the present invention is related to the use of carboxylic acids of Formula (I) to modulate, notably to inhibit the activity of PTPs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.