Pharmaceutical preparation and method of treatment of human malignancies with arginine deprivation
US7951366B2 · kind B2 · utility
3Cited by
3References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 20, 2003 |
| Grant date | May 31, 2011 |
| Priority date | — |
| Expiry date | Jun 20, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides an isolated and substantially purified recombinant human arginase having sufficiently high enzymatic activity and stability to maintain Adequate Arginine Depletion in a patient. The present invention also provides a pharmaceutical composition comprising the modified invention enzyme and method for treatment of diseases using the pharmaceutical composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.