Process for activation of drugs in a vibrational mill
US7951399B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 27, 2002 |
| Grant date | May 31, 2011 |
| Priority date | — |
| Expiry date | Jun 22, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/146
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process is described for the activation (increase in solubility and bioavailability) of drugs. The process, carried out in a vibrational mill, is characterised by the use of given proportions between the physical mixture made up of drug and pharmaceutical carrier and the empty volume among the grinding means contained inside the mill. The process leads to obtaining powders for pharmaceutical use in which the drug has a high and constant degree of activation; this result is obtainable irrespective of the nature of the drug and carrier used, and of their weight ratio.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.