Kit for enzymatic deposition of a metal
US7951554B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 17, 2010 |
| Grant date | May 31, 2011 |
| Priority date | — |
| Expiry date | Feb 17, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/975
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides compositions, kits, assemblies of articles and methodology for carrying out processes that permit biological enzymes to act directly on metals and metal particles. In particular, the invention concerns using enzymes to selectively deposit metal to the vicinity of a target molecule. The invention also relates to linking of metals to enzyme substrates, control of enzymatic metal deposition and applications of enzymatic metal deposition to sensitively and selectively detect target molecules such as biomarkers in various biological samples, such as chromogenic immunohistochemical (IHC) detection in situ by using microscopy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.