Imidazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases

US7951818B2 · kind B2 · utility

Assignee

• Galapagos NV · BE

Inventors

• Paul Edwards · Sandwich, GB
• Sébastien Laurent Xavier Martina · Mechelen, BE
• Martin James Inglis Andrews · Mechelen, BE
• Gregory Bar · Mechelen, BE
• Brigitte ALLART · Mechelen, BE
• Andrew Burritt · San Diego, US
• Xueliang Tao · Arlington, US
• Friedrich Kroll · Schneverdingen, DE

Key dates

• Filing date: Nov 30, 2007
• Grant date: May 31, 2011
• Expiry date: May 22, 2028

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel imidazolopyridine compounds are disclosed that have a formula represented by the following:The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, ECM degradation, joint degradation and/or inflammation, and others.