Positive selection of serum proteins for proteomic analysis
US7955810B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Nov 30, 2007 |
| Grant date | Jun 7, 2011 |
| Priority date | — |
| Expiry date | Aug 13, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6803
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to methods and kits for positive selection of species of interest based on peptide/protein sequence from a biological sample. The species of interest may be proteins and/or peptides of interest which may be placed through a mass spectrometer to obtain a blood peptide/protein signature. The blood peptide/protein signature may be used in proteomic analysis. The techniques include but are not limited to the use of collectors comprising nucleic acid molecules to extract a composition that has a lower concentration of a high abundance species of interest from a sample. This limits the level of influence that any collectors species may have on the results of a mass spectra.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.