5′ CpG nucleic acids and methods of use

US7956043B2 · kind B2 · utility

Assignee

• COLEY PHARMACEUTICAL GMBH · DE

Inventors

• Arthur M. Krieg · Wellesley, US
• Marion Jurk · Dormagen, DE
• Jorg Vollmer · Goldkronach, DE
• Eugen Uhlmann · Königstein, DE

Key dates

• Filing date: Dec 11, 2003
• Grant date: Jun 7, 2011
• Expiry date: May 20, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2310/315
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a class of CpG immunostimulatory oligonucleotides containing a 5′TCG motif or a CG at or near the 5′ end that are useful for stimulating an immune response.