System, device, and methods for real-time screening of live cells, biomarkers, and chemical signatures
US7956328B2 · kind B2 · utility
31Cited by
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57Claims
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Key dates
| Filing date | Jul 29, 2009 |
| Grant date | Jun 7, 2011 |
| Priority date | — |
| Expiry date | Nov 17, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/3595
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An ATR-FTIR device and system are described that defect live-cell responses to stimuli and perturbations in real-time. The system and device can monitor perturbations resulting from exposures to various physical, chemical, and biological materials in real-time, as well as those sustained over a long period of time, including those associated with stimuli having unknown modes-of-action (e.g. nanoparticles). The device and system can also be used to identify specific chemical species or substances that profile cellular responses to these perturbations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.