Nozzle pore configuration for intrapulmonary delivery of aerosolized formulations
US7958887B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 8, 2007 |
| Grant date | Jun 14, 2011 |
| Priority date | — |
| Expiry date | Mar 22, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M15/025
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention describes the configuration of a porous sheet for improving the efficiency for generating an aerosol from a liquid formulation. This aerosolized liquid formulation can be used for intrapulmonary delivery of pharmaceutically active drugs and diagnostic agents when said invention is used in conjunction with the appropriate device. The individual pores in each array (defined as the rows and columns of pores for example in a rectangular array) are generated such that there is a discrete or continuous variation in the pore size within the plurality of pores on the sheet. The drug is subsequently aerosolized by forcing the liquid formulation through the pores on the sheet. The resulting aerosol will contain a controlled range of particle sizes defined by the properties of the porous sheet and the liquid formulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.