Pharmaceutical composition for treatment of diabetes and dyslipidemia

US7959954B2 · kind B2 · utility

Assignee

• COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH · IN

Inventors

• Vijai Lakshmi · Lucknow, IN
• Ajet Saxena · Lucknow, IN
• Rajesh Kumar · Winnipeg, CA
• Raghwendra Pal · Lucknow, IN
• Satyawan Singh · Lucknow, IN
• Arvind Kumar Srivastava · Lucknow, IN
• Preeti Tiwari · Lucknow, IN
• Deepak Raina · Lucknow, IN
• Anil Kumar Rastogi · Lucknow, IN
• Mahendra Srivastava · Lucknow, IN
• Ramesh Chandra · Lucknow, IN
• Anju Puri · Lucknow, IN
• Ram Raghubir · Lucknow, IN
• Poonam Gupta · Lucknow, IN
• Narender Tadigoppula · Lucknow, IN
• Brijendra Kumar Tripathi · Lucknow, IN
• Sudhir Srivastava · Eindhoven, NL

Key dates

• Filing date: Sep 11, 2006
• Grant date: Jun 14, 2011
• Expiry date: Sep 11, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D493/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A bioactive fraction obtained from Xylocarpus that is useful for the treatment of diabetes and dyslipidemia. This fraction can be provided in a pharmaceutical composition that is useful as antidiabetic and antidyslipidemic agent, or can be used in a method of treating diabetes and dyslipidemia in a subject. Also, a process for the preparation of bioactive fraction from Xylocarpus. Isomeric xyloccensins and the preparation of such compounds. Also, pharmaceutical compositions comprising a therapeutically effective amount of such isomeric xyloccensins optionally along with one or more pharmaceutically acceptable carriers, additives, lubricant and diluents and the use of such pharmaceutical compositions in a method for treating dyslipidemia.