Bone delivery conjugates and method of using same to target proteins to bone
US7960529B2 · kind B2 · utility
29Cited by
6References
17Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 3, 2010 |
| Grant date | Jun 14, 2011 |
| Priority date | — |
| Expiry date | Jun 3, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y301/03001
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A bone delivery conjugate having a structure selected from the group consisting of: A) X-Dn-Y-protein-Z; and B) Z-protein-Y-Dn-X, wherein X is absent or is an amino acid sequence of at least one amino acid; Y is absent or is an amino acid sequence of at least one amino acid; Z is absent or is an amino acid sequence of at least one amino acid; and Dn is a poly aspartate wherein n=10 to 16. Compositions comprising same and methods of use thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.