Patent · US Active

Small molecule inhibitors of rotamase enzyme activity

US7960570B2 · kind B2 · utility

0Cited by

60References

17Claims

0Family size

Assignee

GliaMed, Inc. · US

Inventors

Gregory S. Hamilton · Catonsville, US
Joseph P. Steiner · Hampstead, US

Key dates

Filing date	Dec 8, 2009
Grant date	Jun 14, 2011
Priority date	—
Expiry date	Dec 8, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to neurotrophic compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.