Fluorescence detection enhancement using photonic crystal extraction
US7961315B2 · kind B2 · utility
10Cited by
16References
23Claims
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Key dates
| Filing date | Jun 15, 2010 |
| Grant date | Jun 14, 2011 |
| Priority date | — |
| Expiry date | Jun 15, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B2006/1213
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Enhancement of fluorescence emission from fluorophores bound to a sample and present on the surface of two-dimensional photonic crystals is described. The enhancement of fluorescence is achieved by the combination of high intensity near-fields and strong coherent scattering effects, attributed to leaky photonic crystal eigenmodes (resonance modes). The photonic crystal simultaneously exhibits resonance modes which overlap both the absorption and emission wavelengths of the fluorophore. A significant enhancement in fluorescence intensity from the fluorophores on the photonic crystal surface is demonstrated.
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