Patent · US Active

Diagnostic assay and method of treatment for miscarriage risk or premature birth involving macrophage inhibitory cytokine-1 (MIC-1)

US7968303B2 · kind B2 · utility

22Cited by

7References

14Claims

0Family size

Assignee

St. Vincent's Hospital Sydney Limited · AU

Inventors

Samuel Norbert Breit · Chatswood, AU
David Brown · Yorba Linda, US

Key dates

Filing date	Feb 24, 2009
Grant date	Jun 28, 2011
Priority date	—
Expiry date	Jun 13, 2029

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/102
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods for diagnosing risk of miscarriage and/or premature birth, foetal abnormalities, cancer (e.g. prostate cancer) and inflammatory disease (e.g. rheumatoid arthritis) are disclosed which involve determining abnormal levels of macrophage inhibitory cytokine-1 (MIC-1) in a body sample or, otherwise, determining the presence of a MIC-1 variant protein. Also disclosed are methods for reducing the risk of miscarriage and/or premature birth in pregnant subjects, and methods for treatment of inflammatory disease and/or cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.