Pyridazinone kinase inhibitors

US7968546B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Swen Hoelder · London, GB
• Gunter Muller · Frankfurt am Main, DE
• Karl Schoenafinger · Alzenau, DE
• David William Will · Schwalbach, DE
• Hans Matter · Langenselbold, DE
• Martin Bossart · Frankfurt am Main, DE
• Cecile Combeau · Fontenay-aux-Roses, FR
• Christine Delaisi · Châteauroux, FR
• Ingrid Sassoon · Villejuif, FR
• Anke Steinmetz · Vitry-sur-Seine, FR
• Didier Benard · Villiers-le-Bel, FR

Key dates

• Filing date: Jan 26, 2009
• Grant date: Jun 28, 2011
• Expiry date: Jan 26, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are compounds of Formula Iwherein X isand R2, R1, A, B, D, E, R9 are as defined herein useful for treating cancers.