Patent · US Active

Process and methods for the preparation of optically active cis-2-hydroxymethyl-4- (cytosin-1'-yl)-1,3-oxathiolane or pharmaceutically acceptable salts thereof

US7968703B2 · kind B2 · utility

1Cited by
4References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 7, 2005
Grant dateJun 28, 2011
Priority date—
Expiry dateJun 17, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/65586
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

There is provided a method for resolving a compound of formula III, in the cis configuration:There is also provided a process for producing optically active compound of formula I or II:wherein: R1, R2, R3 are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.