Method of applying acoustic energy effective to alter transport or cell viability
US7972286B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 2, 2006 |
| Grant date | Jul 5, 2011 |
| Priority date | — |
| Expiry date | Jan 28, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/14532
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for reversibly, or irreversibly, altering the permeability of cells, tissues or other biological barriers, to molecules to be transported into or through these materials, through the application of acoustic energy, is provided. The acoustic energy is applied indirectly to the cells or tissue whose permeability is to be altered, at a frequency and intensity appropriate to alter the permeability to achieve the desired effect, such as the transport of endogenous or exogenous molecules and/or fluid, for drug delivery, measurement of analyte, removal of fluid, alteration of cell or tissue viability or alteration of structure of materials. In the preferred embodiment, the method includes applying the ultrasound in combination with devices for monitoring and/or implementing feedback controls.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.