Patent · US Active

Radiolabelling methods

US7972588B2 · kind B2 · utility

2Cited by
1References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 9, 2005
Grant dateJul 5, 2011
Priority date—
Expiry dateJun 8, 2028

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to radiodiagnostic and radiotherapeutic agents, including biologically active vectors labelled with radionuclides. It further relates to methods and reagents labelling a vector such as a peptide comprising reaction of a compound of formula (I) with a compound of formula (II): R*-L2-N3 (II) or, a compound of formula (III) with a compound of formula (IV) in the presence of a Cu (I) catalyst. The resultant labelled conjugates are useful as diagnostic agents, for example, as radiopharmaceuticals more specifically for use in Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) or for radiotherapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.