Biomarkers for liver fibrotic injury
US7972785B2 · kind B2 · utility
1Cited by
1References
3Claims
0Family size
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Key dates
| Filing date | Jan 23, 2007 |
| Grant date | Jul 5, 2011 |
| Priority date | — |
| Expiry date | Dec 15, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/085
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a method for detecting liver fibrotic injury, including fibrosis and/or cirrhosis, by assaying biological samples for differential expression of at least one gene encoding a protein chosen from SEQ ID NO: 1-SEQ ID NO: 63 and human orthologs thereof, wherein differential expression of at least one gene suggests the presence of liver fibrosis or cirrhosis. The invention also provides a kit containing nucleic acid probes or antibodies for detecting liver fibrosis and/or cirrhosis by assaying the differential expression of proteins encoded by SEQ ID NO: 1-SEQ ID NO: 63 and human orthologs thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.