Transferrin/transferrin receptor-mediated siRNA delivery
US7973019B1 · kind B1 · utility
13Cited by
8References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 2, 2008 |
| Grant date | Jul 5, 2011 |
| Priority date | — |
| Expiry date | Oct 2, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides interfering RNA molecule-ligand conjugates useful as a delivery system for delivering interfering RNA molecules to a cell in vitro or in vivo. The conjugates comprise a ligand that can bind to a transferrin receptor (TfR). Therapeutic uses for the conjugates are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.