Apparatus for stabilizing mechanical, thermal, and optical properties and for reducing the fluorescence of biological samples for optical evaluation
US7973925B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 5, 2008 |
| Grant date | Jul 5, 2011 |
| Priority date | — |
| Expiry date | Jan 26, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/651
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An apparatus is presented in which a sample can be accurately repositioned in a spectroscopic and/or imaging apparatus upon multiple insertions, and where the apparatus can be worn by living subjects for extended periods of time. The apparatus additionally reduces the temperature increase and stabilizes the temperature of the sample upon irradiation with an optical source of excitation. Additionally, the apparatus stabilizes the pressure and critical optical properties of the sample and its interface with the apparatus. Alternatively or additionally, the apparatus can be used to alter and/or substantially reduce fluorescence from targeted fluorophores in the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.