Genetic polymorphisms associated with coronary heart disease, methods of detection and uses thereof
US7977052B2 · kind B2 · utility
2Cited by
0References
41Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 13, 2006 |
| Grant date | Jul 12, 2011 |
| Priority date | — |
| Expiry date | Jun 20, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/172
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is based on the discovery of genetic polymorphisms that are associated with coronary heart disease and in particular stenosis and MI and response to drug treatment. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.