Binding moieties based on shark ignar domains

US7977071B2 · kind B2 · utility

Assignee

• Adalta Pty Ltd. · AU

Inventors

• Stewart Nuttal · Ivanhoe, AU
• Victor Streltsov · Melbourne, AU
• Katherine Griffiths · Melbourne, AU
• Jennifer Ann Carmichael · Melbourne, AU
• Peter Hudson · Inverloch, AU
• Robert Alexander Irving · Melbourne, AU
• Joseph Noozhumurry Varghese · Melbourne, AU
• Miles Mackay Barraclough · Sydney, AU
• David Peter Simmons · Melbourne, AU
• Kylie Anne Henderson · Dover, AU

Key dates

• Filing date: Jun 2, 2005
• Grant date: Jul 12, 2011
• Expiry date: Jun 2, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/565
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to immunoglobulin new antigen receptors (IgNARs) from fish and uses thereof. In particular, the present invention relates to modified IgNAR variable domains and to domains from members of the immunoglobulin superfamily that have been modified to include structural features derived from IgNAR variable domains.