Patent · US Active

Myoglobin as early predictor of myocardial infarction

US7977105B2 · kind B2 · utility

0Cited by

1References

9Claims

0Family size

Assignee

Roche Diagnostics Operations, Inc. · US

Inventors

Georg Hess · Mainz, DE
Hendrik Huedig · Penzberg, DE
Rosemarie Kientsch-Engel · Feldafing, DE
Dietmar Zdunek · Tutzing, DE

Key dates

Filing date	Mar 9, 2010
Grant date	Jul 12, 2011
Priority date	—
Expiry date	Mar 9, 2030

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/324
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Disclosed is a method for diagnosing myocardial infarction in a subject who suffers from acute coronary syndrome and has a cardiac troponin level, which is detectable, but lower than the level that is considered as being indicative for a myocardial infarction. Also disclosed is a method for identifying a subject being susceptible to cardiac intervention, wherein the subject suffers from acute coronary syndrome and has a cardiac troponin level which is detectable, but lower than a level that is considered as being indicative for a myocardial infarction. These methods are based on the determination of myoglobin and, optionally, Heart-type fatty acid binding protein (H-FABP) in a sample of the subject and comparing the amount of myoglobin and, optionally, H-FABP to reference amounts. Also disclosed are kits or devices to carry out the methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.