Alpha-(N-benzenesulfonamido)cycloalkyl derivatives
US7977362B2 · kind B2 · utility
0Cited by
8References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 17, 2010 |
| Grant date | Jul 12, 2011 |
| Priority date | — |
| Expiry date | Mar 17, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are compounds, pharmaceutical compositions containing the compounds, methods for using the compounds and processes for making the compounds. More specifically, the disclosure relates to alpha-(N-benzenesulfonamido)cycloalkyl compounds that may inhibit one or both of: (i) the functioning of a γ-secretase enzyme; or (ii) the production of β-amyloid. Such compounds may be beneficial in the treatment of Alzheimer's disease and other conditions. Representative compounds have the following formula I:wherein: A, R1, and R2 are described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.