Patent · US Expired

Protective solutions for organs

US7977383B2 · kind B2 · utility

1Cited by

6References

7Claims

0Family size

Assignee

DR. FRANZ KOEHLER CHEMIE GMBH · DE

Inventors

Herbert de Groot · Goldkronach, DE
Ursula Rauen · Essen, DE
Gernot Koehler · Ludwigshafen, DE
Wilfried Bruns · Biblis, DE

Key dates

Filing date	May 16, 2003
Grant date	Jul 12, 2011
Priority date	—
Expiry date	Oct 11, 2023

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Described is a protective solution for avoiding ischemic, storage or ischemia/reperfusion to organs, or to isolated cell systems, or to tissue components after perfusion, surgery, transplantation, or cryopreservation and subsequent reperfusion, which contains alkali ions, and if need be also alkaline earth ions as the electrolyte, a buffer e.g. on a histidine derivation basis, as well as a polyol and/or a saccharide, has an osmolarity of about 290 mosm/l to about 350 mosm/l, as well as a pH value of about 6.8 to about 7.4, and to which hydroxamic acid, and/or one or more hydroxamic acid derivatives are added.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.