System and method for differentiation of normal and malignant in vivo liver tissues
US7979107B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Aug 6, 2009 |
| Grant date | Jul 12, 2011 |
| Priority date | — |
| Expiry date | Aug 6, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/4244
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for differentiating malignant in vivo liver tissues from normal in vivo liver tissues of a living subject includes the steps of: (a) illuminating a first area and a second area of in vivo liver tissues of the living subject with a first excitation light, (b) measuring an intensity of fluorescent light emitted from each of the first area and the second area of in vivo liver tissues in response to the first excitation light as a function of wavelength so as to obtain a first and a second fluorescent spectra, respectively, (c) illuminating the first area and the second area of in vivo liver tissues with a second excitation light, (d) measuring an intensity of diffuse light reflected by each of the first area and the second area of in vivo liver tissues in response to the second excitation light as a function of wavelength so as to obtain a first and a second diffused reflectance spectra, respectively, and (e) identifying one of the first area and the second area of in vivo liver tissues as malignant liver tissues and the other one of the first area and the second area of in vivo liver tissues as normal liver tissues, by comparing the first fluorescence spectrum and the second…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.