Therapeutic targeting of escort proteins
US7981410B2 · kind B2 · utility
1Cited by
7References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 13, 2007 |
| Grant date | Jul 19, 2011 |
| Priority date | — |
| Expiry date | Jul 15, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides for inhibition of viral disease by the provision to a mammalian host of antibodies directed against an escort protein likeTsg 101. These proteins appear on the surface of a cell, and thus can be bound by circulating antibodies thereto. By binding escort proteins on the cell surface, budding of viral particles is inhibited. The virus infects the initial cells, but cannot escape that cell to infect the body en masse.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.