Patent · US Active

Method of preparing polyepitope chimeric gene vaccine

US7981601B2 · kind B2 · utility

0Cited by

3References

18Claims

0Family size

Assignees

INSTITUTE OF BASIC MEDICAL SCIENCES · CN
Chinese Academy of Medical Sciences · CN

Inventors

Heng Wang · Walnut Creek, US
Qiliang Cai · Beijing, CN

Key dates

Filing date	Aug 1, 2003
Grant date	Jul 19, 2011
Priority date	—
Expiry date	Jul 9, 2026

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a method for preparing polyepitope chimeric gene vaccines, designated as Epitopes Assemble Library Immunization (EALI). It involves the construction of expression libraries of polyepitope chimeric genes with different sizes and lengths using gene shuffling and random assembly so as to screen polyepitope chimeric gene vaccines. Immunization of the body with the gene libraries of the invention results in the induction of high level of specific antibodies and specific types of cytokines, and protection on the body.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.