Patent · US Active

Polymorphic and amorphous salt forms of squalamine dilactate

US7981876B2 · kind B2 · utility

7Cited by

1References

12Claims

0Family size

Assignee

Ohr Pharmaceutical Inc. · US

Inventors

Eric Chellquist · Conshohocken, US
Mary Doubleday · Snohomish, US
Charles Gilbert · Pottstown, US
Xuehai Zhang · Norristown, US
Michael McLane · Lansdale, US
Kyle Armbruster · Douglassville, US
Roy Levitt · Ambler, US

Key dates

Filing date	Apr 25, 2006
Grant date	Jul 19, 2011
Priority date	—
Expiry date	Jul 31, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07J41/0005
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to select squalamine salts, methods of their synthesis, their therapeutic use and their advantages relating to manufacturing, product stability and toxicity. More specifically, this application is directed to various forms of the dilactate salt of squalamine and their utility in inhibiting neovascularization and endothelial cell proliferation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.