Patent · US Active

6-N-linked heterocycle-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines as 5-HT2C receptor agonists

US7981882B2 · kind B2 · utility

0Cited by

4References

8Claims

0Family size

Assignee

ELI LILLY AND COMPANY · US

Inventors

Karin Briner · Indianapolis, US
Anne Marie Camp · Basingstoke, GB
Alan Cornell · Basingstoke, GB
Michael Philip Mazanetz · Abingdon, GB
Roger Ryan Rothhaar · Reelsville, US
Frantz Victor · Indianapolis, US
Andrew Caerwyn Williams · Reading, GB
Deyi Zhang · Carmel, US

Key dates

Filing date	Sep 1, 2006
Grant date	Jul 19, 2011
Priority date	—
Expiry date	Jun 14, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D409/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides 6-substituted 2,3,4,5-tetrahydro-1H-benzo[d]azepines of Formula I as selective 5-HT2C receptor agonists for the treatment of 5-HT2C associated disorders including obesity, obsessive/compulsive disorder, depression, and anxiety: Formula (I) where: R6 is selected from the group consisting of (a, b, c, d, e) and other substituents are as defined in the specification.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.