Addition salts of angiotensin-converting enzyme inhibitors with no donor acids, a process for their preparation and pharmaceutical compositions containing them
US7981920B2 · kind B2 · utility
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Key dates
| Filing date | Sep 17, 2008 |
| Grant date | Jul 19, 2011 |
| Priority date | — |
| Expiry date | Jan 24, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of formula (I):(A)m·(B)n (I)wherein A represents an angiotensin-converting enzyme inhibitor compound containing at least one salt-forming basic function, B represents a compound containing at least one salt-forming acid function and at least one NO donor group, m represents the number of acid functions of B that have been converted to a salt and n represents the number of basic functions of A that have been converted to a salt,the bond or bonds between A and B being of the ionic type.Medicinal products containing the same which are useful in treating cardiovascular pathologies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.