Tetralin and indane derivatives and uses thereof

US7981923B2 · kind B2 · utility

Assignee

• Roche Palo Alto LLC · US

Inventors

• Ralph New Harris, III · Redwood City, US
• James M. Kress · Raleigh, US
• David Bruce Repke · Palo Alto, US
• Russell Stephen Stabler · Mountain View, US

Key dates

• Filing date: Jan 26, 2010
• Grant date: Jul 19, 2011
• Expiry date: Jan 26, 2030

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula I, II or III:or pharmaceutically acceptable salts thereof,wherein m, n, q, Ar, R1, R2, R3, R4 and R5 are as defined herein. Also provided are methods for preparing, compositions comprising, and methods for using compounds of formulas I-III.