Chemotherapy method using x-rays
US7981928B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 28, 2003 |
| Grant date | Jul 19, 2011 |
| Priority date | — |
| Expiry date | Mar 17, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K41/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating cancer in a human uses x-rays to disrupt a linkage in a complex of a chemotherapeutic agent and a carrier compound comprising a pre-selected element. The complex is administered to the human and then a localized region of cells which contains the cancerous cells is irradiated with line emission x-rays of an energy selected to cause emission of Auger electrons from the pre-selected element of the carrier compound to disrupt the linkage and release the chemotherapeutic agent near the cancer cells. A kit useful for the treatment comprises an x-ray tube capable of emitting monochromatic line emission x-rays and the complex compound. A transfer compound useful in the method comprises a chemotherapeutic agent linked to a carrier compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.