Device for removing leukocytes from blood

US7985337B2 · kind B2 · utility

Assignee

• Membrana GmbH · DE

Inventors

• Frank Heuser · Neerstedt, DE
• Martin König · Günzburg, DE
• Horst-Dieter Lemke · Obernburg, DE
• Bodo Von Harten · Wuppertal, DE

Key dates

• Filing date: Jan 10, 2008
• Grant date: Jul 26, 2011
• Expiry date: Sep 13, 2028

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M1/3633
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A device for reducing the number of leucocytes in blood comprising a plurality of hollow fibers based on organic polymers, whereby the hollow fibers have a lumen and a wall surrounding the lumen, said wall having an internal surface facing the lumen and an external surface, whereby the hollow fibers are arranged in a cylindrical housing with an inlet arrangement and an outlet arrangement and whereby an outer space is formed between the hollow fibers and the housing, which space is accessible for a fluid via the inlet arrangement and the outlet arrangement, characterized in that only the external surfaces of the hollow fibers are accessible for a fluid, that the lumina of the hollow fibers are not accessible for a fluid, that the arrangement of the hollow fibers shows a high degree of order and that the hollow fibers based on organic polymers cause a generation of the complement activation product C5a in a concentration of at least 10 μg per m2 of fiber surface.