Methods of selecting epidermal growth factor receptor (EGFR) binding agents

US7985559B2 · kind B2 · utility

Assignee

• AMGEN INC. · US

Inventors

• Daniel J. Freeman · Newbury Park, US
• Jilin Sun · Thousand Oaks, US
• Kenneth Jung · Newbury Park, US
• Gary Elliott · Thousand Oaks, US
• Robert Radinsky · Thousand Oaks, US

Key dates

• Filing date: Oct 17, 2008
• Grant date: Jul 26, 2011
• Expiry date: Oct 17, 2028

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/04
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present application relates to methods of selecting EGFr binding agents. In certain embodiments, such EGFr binding agents bind to at least a portion of a panitumumab epitope on an EGFr. In certain embodiments, such EGFr binding agents do not bind to a panitumumab epitope on an EGFr.