Tunable, semi-interpenetrating polymer networks (sIPNS) for medicine and biotechnology
US7985601B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 10, 2003 |
| Grant date | Jul 26, 2011 |
| Priority date | — |
| Expiry date | Nov 6, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L27/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a class of semi-interpenetrating polymeric networks that include a linear polymer molecule functionalized with a bioactive moiety. The linear polymer is physically entangled within a matrix based upon a thermo-responsive polymer. The bioactive moiety is, e.g., a therapeutic moiety or a moiety that enhances the interaction of a cell with the polymer network. The polymer networks of the invention are flowable at room temperature, becoming solid or semi-solid at elevated temperatures (e.g., body temperature). The polymer networks are of use as drug delivery vehicles and as matrices for tissue engineering.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.