Process for the preparation of 6-alpha-hydroxy-N-alkylated opiates
US7985858B2 · kind B2 · utility
7Cited by
15References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 2, 2008 |
| Grant date | Jul 26, 2011 |
| Priority date | — |
| Expiry date | May 9, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to the conversion of a 6-keto morphinan to a 6-alpha-hydroxy morphinan in the presence of a ruthenium, rhodium, or iridium asymmetric catalyst and a hydrogen source.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.