Patent · US Expired

Mutant GTP cyclohydrolase II enzymes

US7989189B2 · kind B2 · utility

0Cited by

2References

4Claims

0Family size

Assignee

DSM IP ASSETS B.V. · NL

Inventors

Sybille Ebert · Biberach, DE
Hans-Peter Hohnmann · Soest, DE
Martin Lehmann · Wohlen, CH
Nigel J. Mouncey · Binningen, CH
Markus Wyss · Liestal, CH

Key dates

Filing date	Jul 7, 2005
Grant date	Aug 2, 2011
Priority date	—
Expiry date	Nov 27, 2025

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P3/02
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to modified GTP cyclohydrolase II enzymes that display increased specific activity, and to polynucleotides encoding them. The invention further pertains to vectors comprising these polynucleotides and host cells containing such vectors. The invention provides a method for producing the modified enzyme and a method for producing riboflavin, a riboflavin precursor, FMN, FAD, or a derivative thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.