Vaccine enhancing the protective immunity to hepatitis c virus using plasmid DNA and recombinant adenovirus
US7989425B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Sep 24, 2003 |
| Grant date | Aug 2, 2011 |
| Priority date | — |
| Expiry date | Mar 5, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/24234
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a vaccine enhancing the protective immunity to Hepatitis C virus using plasmid DNA and recombinant adenovirus, more particularly to a vaccine consisting of Δ core-E1-E2 expressing DNA vaccine, nonstructural protein NS3 and NS4 expressing DNA vaccine, nonstructural protein NS5 expressing DNA vaccine and recombinant adenovirus vaccine, and method for administration of the vaccine by priming with the DNA vaccines described above and boosting with the recombinant adenovirus vaccine thereby enhancing the protective immunity to Hepatitis C virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.