Polymorphs of N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide

US7989494B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Murat Acemoglu · Basel, CH
• Joginder S. Bajwa · Elmwood Park, US
• Piotr H. Karpinski · Lincoln Park, US
• Dimitris Papoutsakis · Acton, US
• Joel Slade · Flanders, US
• Frank Stowasser

Key dates

• Filing date: Jun 7, 2007
• Grant date: Aug 2, 2011
• Expiry date: Jan 17, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D209/20
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Polymorphic forms of N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide free base and salts thereof are prepared by various processes.