Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
US7989650B2 · kind B2 · utility
6Cited by
64References
13Claims
0Family size
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Key dates
| Filing date | Nov 20, 2003 |
| Grant date | Aug 2, 2011 |
| Priority date | — |
| Expiry date | Nov 11, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/05
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Metal carbonyls are used to deliver CO to organs to limit post-ischaemic damage. The organ may be extracorporeal, e.g. for use in a transplant, or may be an isolated organ inside or attached to the body but isolated from the blood flow. The carbonyl preferably has one or more other ligands other than CO, such as amino acids, to modulate the CO release property and solubility.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.