Process for the purification of gabapentin
US7989658B2 · kind B2 · utility
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1References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 15, 2005 |
| Grant date | Aug 2, 2011 |
| Priority date | — |
| Expiry date | Nov 28, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C227/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process for the purification of gabapentin. The process relates to the addition of hydrochloric acid to an aqueous solution or suspension of gabapentin, before, during or after the concentration step of that solution, and the subsequent slurry of the gabapentin by the addition of an alcoholic solvent. The so obtained gabapentin has an high purity degree and, in particular, is characterized by a low content of lactam.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.