Stable lipid-comprising drug delivery complexes and methods for their production
US7993672B2 · kind B2 · utility
59Cited by
140References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 14, 2009 |
| Grant date | Aug 9, 2011 |
| Priority date | — |
| Expiry date | Dec 14, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/88
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel stable, concentrated, biologically active and ready-to-use lipid-comprising drug delivery complexes and methods for their production are described. The biological activity of the complexes produced are comparable to the formulations prepared according to the prior art admixture method and upon purification, the complexes produced by the method of this invention are 50 to 500 fold more concentrated than the complexes formed by admixture. The method described herein provides for the large scale production of lipid-comprising drug delivery systems useful for gene therapy and other applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.