Patent · US Active

Hyaluronic acid derivatives

US7993678B2 · kind B2 · utility

4Cited by

1References

15Claims

0Family size

Assignee

NOVOZYMES BIOPOLYMER A/S · DK

Inventors

Kristoffer Tømmeraas · Bunkeflostrand, SE
Corinne Eenschooten

Key dates

Filing date	Aug 26, 2006
Grant date	Aug 9, 2011
Priority date	—
Expiry date	Apr 24, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2800/413
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the modification of hyaluronic acid (HA) with aryl/alkyl succinic anhydrides (ASA) to produce aryl/alkyl succinic anhydride HA derivatives, to the derivatives as such, and to their applications and uses, particularly in the cosmetic and biomedical industries. The ASA-HA derivatives are expected to have interesting properties that can be used for advanced formulation (bind stronger to the skin compared to non-modified HA), possibly also in delivery systems for actives or drugs by encapsulation (nano/micro capsules) or formation of nano/micro spheres. Further, the low MW ASA-HA derivatives are expected to penetrate the skin more efficiently than non-modified HA of the same MW.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.