Precircle probe nucleic acid amplification methods
US7993880B2 · kind B2 · utility
34Cited by
48References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 19, 2010 |
| Grant date | Aug 9, 2011 |
| Priority date | — |
| Expiry date | Feb 19, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/686
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention is directed to novel methods of multiplexing nucleic acid reactions, including amplification, detection and genotyping. The invention relies on the use of precircle probes that are circularized in the presence of the corresponding target nucleic acids, cleaved, and then amplified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.