Methods of producing pancreatic hormones
US7993920B2 · kind B2 · utility
102Cited by
28References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 12, 2010 |
| Grant date | Aug 9, 2011 |
| Priority date | — |
| Expiry date | Apr 12, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are methods of producing pancreatic hormone-expressing cells by first differentiating pluripotent cells in cell culture so as to produce endodermal cells, the endodermal cells being competent to further differentiate into hormone-expressing cells capable of secreting at least one pancreatic hormone in response to a physiological signal, and then, transplanting the cultured endodermal cells into an organism, such as an organism in need of an endocrine cell therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.