c-Kit kinase inhibitor
US7994159B2 · kind B2 · utility
18Cited by
32References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 10, 2004 |
| Grant date | Aug 9, 2011 |
| Priority date | — |
| Expiry date | Jul 15, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D215/48
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
It was discovered that a compound represented by the general formula (I) shows strong c-Kit kinase inhibitory activity, and it inhibits proliferation of c-Kit kinase activated-cancer cells in vitro and in vivo. A novel anticancer agent showing c-Kit kinase inhibitory activity was discovered.The general formula (I):(wherein R1 represents methyl etc., R2 represents cyano etc., R3 represents hydrogen etc., R4 represents hydrogen etc.).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.