Bacterial efflux pump inhibitors for the treatment of ophthalmic and otic infections

US7994225B2 · kind B2 · utility

Assignee

• REMPEX PHARMACEUTICALS, INC. · US

Inventors

• Keith A. Bostian · Menlo Park, US
• Tomasz Glinka · Sunnyvale, US
• Olga Lomovskaya · Mill Valley, US
• Mark William Surber · San Diego, US
• Neil Berkley · San Diego, US
• David C. Griffith · San Marcos, US

Key dates

• Filing date: Sep 17, 2007
• Grant date: Aug 9, 2011
• Expiry date: Mar 14, 2030

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Efflux pump inhibitors are co-administered with antimicrobial agents for the treatment of ophthalmic or otic infections. The agents may be co-administered directly to the site of infection (e.g., the eye or ear).