Protease resistant interferon beta mutants
US7998469B2 · kind B2 · utility
6Cited by
51References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 13, 2007 |
| Grant date | Aug 16, 2011 |
| Priority date | — |
| Expiry date | May 13, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions of modified cytokines and uses thereof generated using processes and systems for the high throughput directed evolution of peptides and proteins, particularly cytokines that act in complex biological settings, are provided. Also provided are modified cytokines formulated for oral delivery and uses thereof to treat diseases and conditions mediated by cytokines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.